ABSTRACT
INTRODUCTION: The ultra-modern new coronavirus disease (COVID-19) outbreak, that's resulting from the excessive acute breathing syndrome coronavirus 2 (SARS-CoV2), is seeing a dramatic upward thrust in inflamed people all around the world. In the aetiology and scientific signs of SARS-CoV2, the host immune reaction seems to be crucial. In sufferers with excessive COVID-19, SARS-CoV2 now no longer handiest turns on antiviral immune responses, however it could additionally cause out of control inflammatory responses characterized with the aid of using excessive ranges of pro-inflammatory cytokines, ensuing in lymphopenia, lymphocyte dysfunction, and granulocyte and monocyte abnormalities. These immunological abnormalities resulting from SARS-CoV2 may want to cause microbial infections, septic shock, and excessive a couple of organ failure. As a result, the approaches underlying immunological abnormalities in COVID-19 sufferers want to be explored if you want to manual scientific care of the disease. Furthermore, sensible law of SARS-CoV2 immune responses, which incorporates growing antiviral immunity at the same time as restricting systemic inflammation, will be important to a hit treatment. CONCLUSION: SARS-CoV2 has produced a global public health emergency, which promotes greater efforts to assess viral transmission, pathogenesis, and immune responses, as well as improve disease prevention and treatment strategies. Data from these scientific endeavors have shown that managing the interaction between the virus and the immune system is important in reducing morbidity and mortality, in addition to opening up the development of vaccines and vaccination processes. © The Electrochemical Society